Year: 2021 | Month: February | Volume 11 | Issue 1
Differential Expression Profiling of Myogenic Regulatory Factor Genes in Postnatal Longissimus dorsi Muscle of Indigenous and Large White Yorkshire Breeds of Pigs
Cammey
Simrinder Singh Sodhi
R.S. Sethi
Ramneek
DOI:10.30954/2277-940X.01.2021.2
Abstract:
Pigs form a very important component of the Indian livestock. It has immense potential to ensure nutritional and economic security for the weaker sections of the society. Pork is a nutritious food that is commonly consumed worldwide. The current study was planned to investigate the distinction in the relative expression of myogenic regulatory factors (MRF) genes (MyoD, Myf5, Myf6, Pax7 and Pax3) and their role in the postnatal myogenesis Longissimus dorsi muscles of indigenous and Large White Yorkshire (LWY) breeds. These genes help in muscle differentiation and regeneration of skeletal muscles. MyoD has shown significantly (P<0.05) higher quantitative transcript levels in indigenous pigs than in LWY. There is no significant difference in the transcript levels of Myf5 and Myf6 have been observed in the indigenous pigs whereas both the genes have shown significantly (P<0.05) higher quantitative transcript levels in LWY. Further, no statistically significant (P<0.05) difference for Pax3 and Pax7 have been recorded for both the breeds. The current study on relative expression of transcript levels of MRFs in LWY and indigenous pigs presents them as candidate genes for body growth rate. The current study will aid in understanding the genetic basis for myogenesis in postnatal stage. Moreover, it may act as steppingstone for the identification of marker genes related to body growth and meat quality in indigenous breeds.
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